Neem has been used in India for thousands of years.
The oil of the neem tree (Azadirachta indica) has been a popular folk medicine for thousands of years, particularly in India, where neem oil is famous for its antibacterial, antifungal, antioxidant, anti-inflammatory and antiviral properties. Today, neem sees continued use in alternative medicine as a remedy for a multitude of ailments, including oral and skin diseases, ulcers, arthritis and heart disease. Although neem oil is safe and potentially beneficial for some external uses, it can also have serious side effects, especially when taken internally. Therefore, you should consult your doctor before using neem therapeutically.
Toxicity in Children
Neem oil is not safe for infants and children. Serious side effects of neem ingestion in children include vomiting, loose stools, drowsiness, overly acidic blood, anemia, seizures, loss of consciousness and coma. These symptoms are very similar to those of Reye's syndrome, which is a severe and potentially fatal disorder involving swelling of the brain, liver and other organs.
Reproductive Effects
Men and women who are trying to conceive should not take neem internally, because two of its components --- sodium nimbinate and sodium nimbidinate --- have contraceptive qualities and may damage sperm. Pregnant women should never use neem, as sodium nimbinate and sodium nimbidinate can also cause miscarriages.
Drug Interactions
If you are taking prescription medications, it is imperative that you speak with your doctor before using neem.
Do not take neem internally or topically if you are taking lithium. Neem changes the way the body processes lithium, and may increase the likelihood of negative side effects. Because neem stimulates the immune system, it may also interfere with immunosuppressant drugs that treat autoimmune diseases like multiple sclerosis, lupus and rheumatoid arthritis. Neem may also intensify the symptoms of autoimmune diseases.
Low Blood Sugar (Hypoglycemia)
Discontinue the use of neem well in advance of surgery.
Do not use neem if you're taking diabetes medication, as neem may reduce blood sugar levels. If you have diabetes and still want to use neem, be sure to let your doctor know, and take care to monitor your blood sugar frequently. Because doctors need to monitor the blood sugar levels of surgical patients, you should not use neem for at least two weeks before and after surgery. If you are using neem and plan to have surgery, notify your doctor.
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